Anti-p57 Kip2 Rabbit Monoclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:50 dilution.
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer, using the Antibody at 1:50 dilution.
Immunohistochemical analysis of paraffin-embedded Human tongue cancer, using the Antibody at 1:50 dilution.
Western blot analysis on HeLa cell using p57 Kip2 Antibody.
Immunohistochemical analysis of paraffin-embedded rat kidney, using p57 Kip2 Antibody.
Immunofluorescent analysis of HeLa cells treated with dexamethasone, using p57 Kip2 Antibody.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC, IF, ICC, IP
Primary Accession	P49918
Host	Rabbit
Isotype	IgG
Reactivity	Rat, Human, Mouse
Clonality	Monoclonal
Format	Liquid
Description	Anti-p57 Kip2 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Additional Information
Gene ID	1028
Other Names	Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2
Calculated MW	32177 Da
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50
Source	Eukaryota
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names	Clone: 17C19
Immunogen	A synthesized peptide derived from human p57 Kip2
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	CDKN1C
Synonyms	KIP2
Function	Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Cellular Location	Nucleus.
Tissue Location	Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.