癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-VEGF (Bevacizumab), humanized Antibody
Human Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| E |
|---|---|
| Primary Accession | AAP86646 |
| Reactivity | Human |
| Host | Human |
| Clonality | Monoclonal |
| Isotype | Human IgG1 |
| Application & Usage | Neutralization: 0.1-20 µg/ml, ELISA: 2 µg/ml |
|---|---|
| Alias Symbol | VEGF |
| Other Names | Avastin |
| Appearance | Colourless liquid |
| Formulation | 100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-VEGF (Bevacizumab), humanized Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Bevacizumab (Avastin) is a recombinant humanized monoclonal IgG1 antibody. Bevacizumab, targets the cell surface protein called vascular endothelial growth factor (VEGF) results in suppression of tumor growth. VEGF plays an essential role in developmental angiogenesis and is also important for reproductive and bone angiogenesis. Avastin is used to treat various cancers like metastatic colorectal cancer, non-squamous non-small cell lung cancer, metastatic breast cancer, glioblastoma and metastatic renal cell carcinoma.
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