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>   首页   >   产品   >   一抗   >   癌症   >   Anti-EGFR (Cetuximab), Chimeric Antibody   

Anti-EGFR (Cetuximab), Chimeric Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
E
Primary Accession AAI18666
Reactivity Human
Host Human/Mouse Chimeric
Clonality Monoclonal
Isotype Human IgG1
Additional Information
Application & Usage Neutralization : 1-20 µg/ml; ELISA: 2 µg/ml
Alias Symbol EGFR
Other Names Erbitux, ErbB1
Appearance Colourless liquid
Formulation 100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-EGFR (Cetuximab), Chimeric Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Research Areas

BACKGROUND

Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody. Epidermal growth factor receptor (EGFR) is a receptor found on both normal and tumor cells that is important for cell growth. Cetuximab is an EGFR inhibitor, used to treat cancer by blocking the activity of EGFR and keep cancer from growing. Cetuximab can form a bridge that trigger an immune response by binding to the EGFR on the tumor cells. It is used for the treatment of EGFR-expressing, metastatic colorectal cancer.

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