癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FSCN1 Monoclonal Antibody
Mouse Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, FC, ICC, E |
|---|---|
| Primary Accession | NP_003079 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b, k |
| Positive Control | WB, ICC/IF, Flow cytometry |
|---|---|
| Application & Usage | WB: 1:1000, ICC/IF: 1:100, Flow cytometry: 2-5ug for 1x106 cells, ELISA |
| Alias Symbol | FSCN1 |
| Other Names | FAN1, HSN, SNL |
| Appearance | Colourless liquid |
| Formulation | 50 µg (1mg/ml) of antibody in PBS, pH 7.4 with 0.02% Sodium Azide, 10% Glycerol |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | FSCN1 Monoclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.
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