癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Beta-galactosidase, Human IgG1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, FC |
|---|---|
| Primary Accession | P16278 |
| Host | Recombinant |
| Clonality | Monoclonal |
| Isotype | Human IgG1, lambda |
| Calculated MW | 76075 Da |
| Gene ID | 2720 |
|---|---|
| Alias Symbol | GLB1 |
| Other Names | beta-gal; Acid beta galactosidase; Beta galactosidase 1; β-galactosidase; β-gal; EBP; ELNR1; Galactosidase beta 1; GLB1; MPS4B |
| Appearance | Colorless liquid |
| Formulation | 200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300 |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-Beta-galactosidase, Human IgG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GLB1 (HGNC:4298) |
|---|---|
| Synonyms | ELNR1 |
| Function | [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. |
| Cellular Location | [Isoform 1]: Lysosome |
| Tissue Location | Detected in placenta (at protein level) (PubMed:8383699). Detected in fibroblasts and testis (PubMed:2511208) |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Isoform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers
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