癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-p38 MAPK Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q16539, Q15759, P53778 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Positive Control | WB: human breast cancer tissue; IHC: HeLa cell lysates |
|---|---|
| Application & Usage | IHC: 1:1000 -1:5000 dilution; WB: 1:1000 - 1:2000 dilution. |
| Alias Symbol | MAPK14 |
| Other Names | Mitogen-activated protein kinase 14, MK14, Mapk14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, CRK1, Csbp1, Csbp2, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX--interacting protein 2, MAP kinase MXI2, SAPK2A |
| Appearance | Colorless liquid |
| Formulation | In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-p38 MAPK Rabbit Monoclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cell cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.
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