癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Phospho-HSP20 (Ser16) Antibody
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC, IF, ICC |
|---|---|
| Primary Accession | O14558 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 17136 Da |
| Gene ID | 126393 |
|---|---|
| Positive Control | WB: MCF7, HEK293, NIH3T3, H9C2 cell lysates; IHC: human breast cancer tissue; IFC: HEK293 cells |
| Application & Usage | WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100 |
| Alias Symbol | HSPB1 |
| Other Names | Heat shock protein beta-6; HspB6; Heat shock 20 kDa-like protein p20 |
| Appearance | Colorless liquid |
| Formulation | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Phospho-HSP20 (Ser16) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSPB6 |
|---|---|
| Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
| Cellular Location | Cytoplasm. Nucleus. Secreted Note=Translocates to nuclear foci during heat shock |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Activation of cyclic nucleotide-dependent signaling pathways leads to phosphorylation of the small heat shock-related protein, HSP20, on serine 16, and relaxation of vascular smooth muscle.
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Discontinued
Cat# ABV11847
Size:
100 µl
Price:
¥ 3,900.00
替代产品:
