癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-FNBP3 Antibody
Rabbit Polyclonal antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | O75400 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 108805 Da |
| Gene ID | 55660 |
|---|---|
| Positive Control | WB: HeLa, mouse brain, rat brain lystes |
| Application & Usage | WB; 1:500 – 1:2000 |
| Alias Symbol | PRPF40A |
| Other Names | FBP11, FLAF1, FNBP3; HIP10, HYPA, Pre-mRNA-processing factor 40 homolog A, Fas ligand-associated factor 1, Formin-binding protein 11, Formin-binding protein 3, Huntingtin yeast partner A, Huntingtin-interacting protein 10, HIP-10, Huntingtin-interacting protein A, Renal carcinoma antigen NY-REN-6 |
| Formulation | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Reconstitution & Storage | 12 months under -20°C |
| Background Descriptions | |
| Precautions | Anti-FNBP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PRPF40A |
|---|---|
| Synonyms | FBP11, FLAF1, FNBP3, HIP10, HYPA |
| Function | Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. |
| Cellular Location | Nucleus speckle. Nucleus matrix. Note=Colocalizes with AKAP8L in the nuclear matrix. |
| Tissue Location | Expressed in the brain cortex (at protein level). Widely expressed. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing
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