癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-TRAK2 Antibody
Rabbit Polyclonal antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC |
|---|---|
| Primary Accession | O60296 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 101419 Da |
| Gene ID | 66008 |
|---|---|
| Positive Control | WB: HepG2, mouse heart, rat heart lysates; IHc: human breast cancer tissue |
| Application & Usage | WB; 1:500 – 1:2000, IHC; 1:50 – 1:200 |
| Alias Symbol | TRAK2 |
| Other Names | ALS2CR3, KIAA0549, Trafficking kinesin-binding protein 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein |
| Formulation | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
| Reconstitution & Storage | 12 months under -20°C |
| Background Descriptions | |
| Precautions | Anti-TRAK2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TRAK2 |
|---|---|
| Synonyms | ALS2CR3, KIAA0549 |
| Function | May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. |
| Cellular Location | Cytoplasm. Early endosome. Mitochondrion. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity) |
| Tissue Location | Widely expressed, with highest expression in heart. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Trafficking kinesin-binding protein 2 regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
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