癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-ZNT2 Antibody
- 产品详情
- 实验流程
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9BRI3 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Calculated MW | 40564 Da |
| Gene ID | 7780 |
|---|---|
| Positive Control | WB: HeLa, RAW264.7, PC12 cell lystae; IHC: human lung cancer |
| Application & Usage | WB; 1:500 – 1:2000, IHC; 1:50 – 1:200 |
| Other Names | ZNT2, Zinc transporter 2, ZnT-2, Solute carrier family 30 member 2 |
| Target/Specificity | SLC30A2 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Handling | The antibody solution should be gently mixed before use |
| Reconstitution & Storage | -20°C |
| Background Descriptions | |
| Precautions | Anti-ZNT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLC30A2 (HGNC:11013) |
|---|---|
| Function | [Isoform 1]: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity (PubMed:17065149, PubMed:21289295, PubMed:22733820, PubMed:25657003, PubMed:25808614, PubMed:30893306). Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells (PubMed:19496757). By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution (PubMed:25808614). |
| Cellular Location | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Zymogen granule membrane {ECO:0000250|UniProtKB:Q2HJ10}; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein. Note=Localization to lysosomes is induced by TNF |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# ABV11926
