癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Alanine Racemase Antibody
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P10724 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43593 Da |
| Positive Control | Western blot |
|---|---|
| Application & Usage | Western blot: 1-4 µg |
| Other Names | Alanine Racemase Y354N, alr, dal |
| Target/Specificity | Alanine Racemase |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-Alanine Racemase Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | alr |
|---|---|
| Synonyms | dal |
| Function | Catalyzes the interconversion of L-alanine and D-alanine. Also weakly active on serine. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Mutant Alanine Racemase (Y354N) (mAR-Y354N), a pyridoxal 5- phosphate (PLP) dependent enzyme catalyzes the interconversion of the L-Serine to D-Serine. In WT Alanine Racemase Tyr354 plays a crucial role in defining the strict specificity of AR for alanine, in converting L-Alanine to D-Alanine, which is an important component of the peptidoglycan layer of bacterial cell wall. By mutating the active site Tyr 354 to Asn, the specificity of the enzyme changes and it becomes a racemase with dual specificity for L- Alanine and L-Serine.
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