GATA3
Rabbit Monoclonal antibody(Mab)
- 产品详情
- 实验流程
Application ![]()
| IHC-P |
---|---|
Primary Accession | P23771 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 255B6B8 |
Calculated MW | 47916 Da |
Gene ID | 2625 |
---|---|
Gene Name | GATA3 |
Other Names | Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3 |
Dilution | IHC-P~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C. |
Precautions | GATA3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GATA3 |
---|---|
Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages. |
Cellular Location | Nucleus. |
Tissue Location | T-cells and endothelial cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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