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>   首页   >   产品   >   免疫组化   >   免疫组化抗体   >   GATA3   

GATA3

Rabbit Monoclonal antibody(Mab)

     
  • 14 - GATA3 AD80077
    乳腺癌
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession P23771
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 255B6B8
Calculated MW 47916 Da
Additional Information
Gene ID 2625
Gene Name GATA3
Other Names Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3, GATA3
Dilution IHC-P~~Ready-to-use
StorageMaintain refrigerated at 2-8°C.
Precautions GATA3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA3
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
Cellular Location Nucleus.
Tissue Location T-cells and endothelial cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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