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>   首页   >   产品   >   免疫组化   >   免疫组化抗体   >   Lambda链   

Lambda链

Mouse Monoclonal antibody(Mab)

     
  • 14 - Lambda链 AD80089
    扁桃体
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession P01701
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 700F2F8
Calculated MW 12249 Da
Additional Information
Gene Name IGLC1 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.6}
Other Names Immunoglobulin lambda variable 1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}, Ig lambda chain V-I region BL2, Ig lambda chain V-I region EPS, Ig lambda chain V-I region NEW, Ig lambda chain V-I region NIG-64, IGLV1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}
Dilution IHC-P~~Ready-to-use
StorageMaintain refrigerated at 2-8°C.
Precautions Lambda Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGLV1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}
Function V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins- secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location Secreted. Cell membrane
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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