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CD10 Antibody

Mouse Monoclonal Antibody (Mab)

     
  • 2 - CD10 Antibody AD80166
    Immunohistochemical analysis of paraffin-embedded human kidney tissue using AD80166 performed on the Abcarta® FAIP-48 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:ADR005) was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P08473
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 453F9G7
Calculated MW 85514 Da
Additional Information
Gene ID 4311
Gene Name MME
Other Names Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
Dilution IHC~~Ready-to-use
StorageMaintain refrigerated at 2-8°C.
Precautions CD10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MME {ECO:0000303|PubMed:27588448, ECO:0000312|HGNC:HGNC:7154}
Function Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:6208535, PubMed:6349683, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991, PubMed:6349683). Catalyzes cleavage of bradykinin, substance P and neurotensin peptides (PubMed:6208535). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675, PubMed:6349683). Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)) (PubMed:16254193, PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).
Cellular Location Cell membrane; Single-pass type II membrane protein
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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