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CD123 Antibody

Mouse Monoclonal Antibody (Mab)

     
  • 2 - CD123 Antibody AD80236
    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using AD80236 performed on the Abcarta® FAIP-48 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a Citrate buffer (pH6. 0).Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:ADR005) was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P26951
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 533A2D3
Calculated MW 43330 Da
Additional Information
Gene ID 3563
Gene Name IL3RA
Other Names Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R
Dilution IHC~~Ready-to-use
StorageMaintain refrigerated at 2-8°C.
Precautions CD123 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL3RA (HGNC:6012)
Synonyms IL3R
Function Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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