Anti-SOX-10 antibody

Rabbit Monoclonal antibody(Mab)

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human melanoma tissue was performed with SOX-10 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human melanoma tissue was performed with SOX-10 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human melanoma tissue was performed with SOX-10 primary antibody, followed by peroxidase-conjugated secondary antibody and DAB staining.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	IHC-P
Primary Accession	P56693
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Clone Names	908G6C7
Calculated MW	49911 Da

Additional Information
Gene ID	6663
Gene Name	SOX10
Other Names	Transcription factor SOX-10, SOX10
Dilution	IHC-P~~Pre-diluted Ready-To-Use (RTU)
Storage	Maintain refrigerated at 2-8°C.
Precautions	SOX-10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name	SOX10
Function	Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Cellular Location	Cytoplasm. Nucleus. Mitochondrion outer membrane {ECO:0000250\|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250\|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250\|UniProtKB:Q04888}
Tissue Location	Expressed in fetal brain and in adult brain, heart, small intestine and colon

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.