CD123
Rabbit Monoclonal antibody(Mab)
- 产品详情
- 实验流程
Application ![]()
| IHC-P |
---|---|
Primary Accession | P26951 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 525I4C1 |
Calculated MW | 43330 Da |
Gene ID | 3563 |
---|---|
Other Names | Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA (HGNC:6012), IL3R |
Dilution | IHC-P~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C. |
Name | IL3RA (HGNC:6012) |
---|---|
Synonyms | IL3R |
Function | Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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