Goat anti-ABCD3, Biotinylated Antibody
Peptide-affinity purified goat antibody
- 产品详情
- 实验流程
Application ![]()
| WB, IHC, Pep-ELISA |
---|---|
Primary Accession | P28288 |
Other Accession | NP_002849.1 |
Reactivity | Human, Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Clone Names | ABCD3 |
Calculated MW | 75476 Da |
Gene ID | 5825 |
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Other Names | ABCD3; ATP binding cassette subfamily D member 3; ABC43; CBAS5; PMP70; PXMP1; ZWS2; 70 kDa peroxisomal membrane protein; ATP-binding cassette, sub-family D (ALD), member 3; Peroxisomal membrane protein-1 (70kD); dJ824O18.1 (ATP-binding cassette, sub-famil |
Dilution | WB~~1:1000 IHC~~1:100~500 Pep-ELISA~~N/A |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | This antibody is expected to recognize one isoform (NP_002849.1) only. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-ABCD3, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ABCD3 (HGNC:67) |
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Function | Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long- chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched- chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed:11248239, PubMed:24333844, PubMed:25168382, PubMed:29397936). Has fatty acyl-CoA thioesterase and ATPase activities (PubMed:29397936). Probably hydrolyzes fatty acyl- CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity). Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:24333844, PubMed:25944712). |
Cellular Location | Peroxisome membrane; Multi-pass membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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