癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Goat anti-OCIL Antibody
Peptide-affinity purified goat antibody
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, FC, Pep-ELISA |
|---|---|
| Primary Accession | Q9UHP7 |
| Other Accession | NP_037401.1, NP_001004419.1, NP_001184246.1 |
| Reactivity | Human, Dog, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | CLEC2D |
| Calculated MW | 21849 Da |
| Gene ID | 29121 |
|---|---|
| Other Names | CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin related f; C-type lectin superfamily 2, member D; lectin-like NK cell receptor; lectin-like transcript 1; osteoclast inhibitory lectin |
| Dilution | WB~~1:1000 IHC~~1:100~500 IF~~1:50~200 FC~~1:10~50 Pep-ELISA~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize all isoforms (NP_037401.1; NP_001004419.1; NP_001184246.1). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-OCIL Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CLEC2D |
|---|---|
| Synonyms | CLAX, LLT1, OCIL |
| Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:16339513, PubMed:20843815). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein [Isoform 4]: Endoplasmic reticulum |
| Tissue Location | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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