癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Goat anti-EDF1 / MBF1 Antibody
Peptide-affinity purified goat antibody
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, FC, Pep-ELISA |
|---|---|
| Primary Accession | O60869 |
| Other Accession | NP_003783.1, NP_694880.1, NP_001268226.1, NP_001268227.1, NP_001268228.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | EDF1 |
| Calculated MW | 16369 Da |
| Gene ID | 8721 |
|---|---|
| Other Names | EDF1; MBF1; EDF-1; MGC9058; endothelial differentiation-related factor 1; multiprotein bridging factor 1 |
| Dilution | WB~~1:1000 IHC~~1:100~500 IF~~1:50~200 FC~~1:10~50 Pep-ELISA~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-EDF1 / MBF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | EDF1 |
|---|---|
| Function | Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. |
| Cellular Location | Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin |
| Tissue Location | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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