癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Goat Anti-Scribble / Vartul Antibody
Peptide-affinity purified goat antibody
- 产品详情
- 实验流程
Application 
| IHC, Pep-ELISA |
|---|---|
| Primary Accession | C0HLS1 |
| Other Accession | NP_874365.2, NP_056171.2 |
| Reactivity | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | SCRIB |
| Calculated MW | 11984 Da |
| Other Names | SCRIB, scribbled homolog (Drosophila), Circletail homolog (Mouse), CRIB1, SCRB1, SCRIB1, Vartul, KIAA0147, scribble |
|---|---|
| Dilution | IHC~~1:100~500 Pep-ELISA~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Immunogen | Peptide with sequence C-VRPGRRGLGPVPS, from the C Terminus of the protein sequence according to NP_874365.2; NP_056171.2. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-Scribble / Vartul Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SCRIB {ECO:0000303|PubMed:34535749} |
|---|---|
| Function | Represses translation of the downstream SCRIB protein (PubMed:34535749). Translation of oSCRIB hinders SCRIB translation but does not completely abolish it, probably due to leaky scanning which allows the ribosome to bypass the weaker oSCRIB start codon and initiate translation at the stronger SCRIB start codon (PubMed:34535749). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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