癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-IDH1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | O75874 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2105 |
| Calculated MW | 46659 Da |
| Gene Name | IDH1 |
| Aliases | IDH1; Isocitrate Dehydrogenase (NADP(+)) 1; Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic; Isocitrate Dehydrogenase 1 (NADP+), Soluble; Isocitrate Dehydrogenase [NADP] Cytoplasmic; Oxalosuccinate Decarboxylase; NADP(+)-Specific ICDH; EC 1.1.1.42; PICD; IDH; NADP-Dependent Isocitrate Dehydrogenase, Peroxisomal; NADP-Dependent Isocitrate Dehydrogenase, Cytosolic; Epididymis Secretory Sperm Binding Protein; Cytosolic NADP-Isocitrate Dehydrogenase; Isocitrate Dehydrogenase 1 (NADP+); Epididymis Secretory Protein Li 26; Epididymis Luminal Protein 216; HEL-S-26; HEL-216; IDCD; IDPC; IDPc; IDP |
| Immunogen | A synthesized peptide derived from human IDH1 |
| Gene ID | 3417 |
|---|---|
| Other Names | Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, PICD |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | IDH1 |
|---|---|
| Synonyms | PICD |
| Function | Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed:10521434, PubMed:19935646). Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (PubMed:10521434). May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity). |
| Cellular Location | Cytoplasm, cytosol. Peroxisome |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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