癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-PACSIN3 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q9UKS6 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 25GB500 |
| Calculated MW | 48487 Da |
| Gene Name | PACSIN3 |
| Aliases | PACSIN3; Protein Kinase C And Casein Kinase SubstRate In Neurons 3; SDPIII; Protein Kinase C And Casein Kinase SubstRate In Neurons Protein 3; SH3 Domain-Containing Protein 6511; Syndapin III |
| Immunogen | Recombinant protein of human PACSIN3 |
| Gene ID | 29763 |
|---|---|
| Other Names | Protein kinase C and casein kinase substrate in neurons protein 3, SH3 domain-containing protein 6511, PACSIN3 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PACSIN3 |
|---|---|
| Function | Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity). |
| Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the inner aspect of the plasma membrane in myotubes. |
| Tissue Location | Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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