癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-MAP2K3 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P46734 |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2420 Spe cies Reactivity |
| Calculated MW | 39318 Da |
| Gene Name | MAP2K3 |
| Aliases | MAP2K3; Mitogen-Activated Protein Kinase Kinase 3; MEK3; MKK3; Stress-Activated Protein Kinase Kinase 2; MAP Kinase Kinase 3; MAPK/ERK Kinase 3; MAPKK3; SAPKK2; PRKMK3; Dual Specificity Mitogen-Activated Protein Kinase Kinase 3; SAPK Kinase 2; EC 2.7.12.2; SAPKK-2; MAPKK 3; MEK 3; Dual Specificity Mitogen Activated Protein Kinase Kinase 3; SKK2 |
| Immunogen | A synthesized peptide derived from human MEK3 |
| Gene ID | 5606 |
|---|---|
| Other Names | Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, 2.7.12.2, MAPK/ERK kinase 3, MEK 3, Stress-activated protein kinase kinase 2, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, MEK3, MKK3, PRKMK3, SKK2 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MAP2K3 |
|---|---|
| Synonyms | MEK3, MKK3, PRKMK3, SKK2 |
| Function | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. |
| Tissue Location | Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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