癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-p150 CAF1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q13111 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB1060 |
| Calculated MW | 106910 Da |
| Gene Name | CHAF1A |
| Aliases | CAF1P150; CAF1B; CAF-1; CAF1; P150; Chromatin Assembly Factor I P150 Subunit; Chromatin Assembly Factor I (150 KDa); CAF-I 150 KDa Subunit; CAF-1 Subunit A; CAF-I P150; MGC71229; Hp150; Chromatin Assembly Factor 1, Subunit A (P150); CTB-50L17.7; CAF |
| Immunogen | A synthesized peptide derived from human p150 CAF1 |
| Gene ID | 10036 |
|---|---|
| Other Names | Chromatin assembly factor 1 subunit A, CAF-1 subunit A, Chromatin assembly factor I p150 subunit, CAF-I 150 kDa subunit, CAF-I p150, hp150, CHAF1A (HGNC:1910), CAF, CAF1P150 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CHAF1A (HGNC:1910) |
|---|---|
| Synonyms | CAF, CAF1P150 |
| Function | Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. |
| Cellular Location | Nucleus. Note=DNA replication foci |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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