癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-ABHD5 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q8WTS1 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 3260 |
| Calculated MW | 39096 Da |
| Gene Name | ABHD5 |
| Aliases | ABHD5; Antibodyhydrolase Domain Containing 5, Lysophosphatidic Acid Acyltransferase; NCIE2; 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5; Antibodyhydrolase Domain-Containing Protein 5; Lipid Droplet-Binding Protein CGI-58; EC 2.3.1.51; CGI-58; Antibodyhydrolase Domain Containing 5; CGI58; IECN2 |
| Immunogen | A synthesized peptide derived from human ABHD5 |
| Gene ID | 51099 |
|---|---|
| Other Names | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, 2.3.1.51, Abhydrolase domain-containing protein 5, Lipid droplet-binding protein CGI-58, ABHD5 (HGNC:21396), NCIE2 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ABHD5 (HGNC:21396) |
|---|---|
| Synonyms | NCIE2 |
| Function | Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid (PubMed:18606822). Functions preferentially with 1-oleoyl- lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1- stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity). Functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). |
| Cellular Location | Cytoplasm. Lipid droplet {ECO:0000250|UniProtKB:Q9DBL9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DBL9}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). |
| Tissue Location | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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