癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-ACBD3 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9H3P7 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3620 |
| Calculated MW | 60593 Da |
| Gene Name | ACBD3 |
| Aliases | ACBD3; Acyl-CoA Binding Domain Containing 3; GCP60; PBR- And PKA-Associated Protein 7; GOCAP1; GOLPH1; PAP7; Peripheral Benzodiazepine Receptor-Associated Protein PAP7; Acyl-Coenzyme A Binding Domain Containing 3; Golgi Complex Associated Protein 1, 60kDa; Golgi Resident Protein GCP60; Golgi Phosphoprotein 1; Acyl-CoA-Binding Domain-Containing Protein; Golgi Complex-Associated Protein 1; PKA (RIalpha)-Associated Protein |
| Immunogen | A synthesized peptide derived from human ACBD3 |
| Gene ID | 64746 |
|---|---|
| Other Names | Golgi resident protein GCP60, Acyl-CoA-binding domain-containing protein 3, Golgi complex-associated protein 1, GOCAP1, Golgi phosphoprotein 1, GOLPH1, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor-associated protein PAP7, Golgi resident protein GCP60, N-terminally processed, ACBD3, GCP60, GOCAP1, GOLPH1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ACBD3 |
|---|---|
| Synonyms | GCP60, GOCAP1, GOLPH1 |
| Function | Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (PubMed:11590181). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase (PubMed:27009356). |
| Cellular Location | Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Note=Also mitochondrial (via its interaction with PBR). |
| Tissue Location | Ubiquitous, with highest expression in testis and ovary. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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