癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-PWP1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q13610 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2580 |
| Calculated MW | 55828 Da |
| Gene Name | PWP1 |
| Aliases | PWP1; PWP1 Homolog, Endonuclein; IEF-SSP-9502; Periodic Tryptophan Protein 1 Homolog; Keratinocyte Protein IEF SSP 9502; Endonuclein; Nuclear Phosphoprotein Similar To S. Cerevisiae PWP1; PWP1 Homolog (S. Cerevisiae); NCLB |
| Immunogen | A synthesized peptide derived from human PWP1 |
| Gene ID | 11137 |
|---|---|
| Other Names | Periodic tryptophan protein 1 homolog {ECO:0000312|HGNC:HGNC:17015}, Keratinocyte protein IEF SSP 9502, PWP1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PWP1 |
|---|---|
| Function | Chromatin-associated factor that regulates transcription (PubMed:29065309). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309). Regulates the epigenetic status of rDNA (PubMed:29065309). |
| Cellular Location | Nucleus. Nucleus, nucleolus. Chromosome. Note=Associates with chromatin regions of rDNA. |
| Tissue Location | High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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