癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Syntaxin binding protein 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P61764 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2570 |
| Calculated MW | 67569 Da |
| Gene Name | STXBP1 |
| Aliases | STXBP1; Syntaxin Binding Protein 1; MUNC18-1; Syntaxin-Binding Protein 1; UNC18; Protein Unc-18 Homolog 1; Protein Unc-18 Homolog A; Unc-18A; Unc18-1; HUNC18; N-Sec1; RBSEC1; NSEC1; P67; Neuronal SEC1; RbSec1; UNC18A; NSec1; DEE4 |
| Immunogen | A synthesized peptide derived from human STXBP1 |
| Gene ID | 6812 |
|---|---|
| Other Names | Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67, STXBP1, UNC18A |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | STXBP1 |
|---|---|
| Synonyms | UNC18A |
| Function | Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synaptic membranes (By similarity). May play a role in determining the specificity of intracellular fusion reactions. |
| Cellular Location | Cytoplasm, cytosol. Membrane; Peripheral membrane protein |
| Tissue Location | Brain and spinal cord. Highly enriched in axons. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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