癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-MAP2K2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P36507 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB2935 |
| Calculated MW | 44424 Da |
| Gene Name | MAP2K2 |
| Aliases | MAP2K2; Mitogen-Activated Protein Kinase Kinase 2; MEK2; MAP Kinase Kinase 2; PRKMK2; MKK2; Dual Specificity Mitogen-Activated Protein Kinase Kinase 2; ERK Activator Kinase 2; MAPK/ERK Kinase 2; EC 2.7.12.2; Mitogen-Activated Protein Kinase Kinase 2, P45; MAPKK 2; MAPKK2; MEK 2; CFC4 |
| Immunogen | A synthesized peptide derived from human MEK2 |
| Gene ID | 5605 |
|---|---|
| Other Names | Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, 2.7.12.2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2, MAP2K2, MEK2, MKK2, PRKMK2 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MAP2K2 |
|---|---|
| Synonyms | MEK2, MKK2, PRKMK2 |
| Function | Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (PubMed:29433126). |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane localization is probably regulated by its interaction with KSR1. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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