癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-CDC37 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q16543 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3440 |
| Calculated MW | 44468 Da |
| Gene Name | CDC37 |
| Aliases | CDC37; Cell Division Cycle 37, HSP90 Cochaperone; Hsp90 Co-Chaperone Cdc37; P50CDC37; CDC37 (Cell Division Cycle 37, S. Cerevisiae, Homolog); Hsp90 Chaperone Protein Kinase-Targeting Subunit; CDC37 Cell Division Cycle 37 Homolog; CDC37 Cell Division Cycle 37 Homolog (S. Cerevisiae); Cell Division Cycle 37 Homolog (S. Cerevisiae); Cell Division Cycle 37 Homolog; P50Cdc37; CDC37A |
| Immunogen | A synthesized peptide derived from human Cdc37 |
| Gene ID | 11140 |
|---|---|
| Other Names | Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, CDC37, CDC37A |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CDC37 |
|---|---|
| Synonyms | CDC37A |
| Function | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206). |
| Cellular Location | Cytoplasm. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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