癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-CAPG Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P40121 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB3045 |
| Calculated MW | 38499 Da |
| Gene Name | CAPG |
| Aliases | CAPG; Capping Actin Protein, Gelsolin Like; MCP; AFCP; Capping Protein (Actin Filament), Gelsolin-Like; Macrophage-Capping Protein; Epididymis Secretory Protein Li 66; Actin-Regulatory Protein CAP-G; Actin Regulatory Protein CAP-G; Gelsolin-Like Capping Protein; Macrophage Capping Protein; HEL-S-66 |
| Immunogen | A synthesized peptide derived from human CAPG |
| Gene ID | 822 |
|---|---|
| Other Names | Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CAPG |
|---|---|
| Synonyms | AFCP, MCP |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
| Cellular Location | Nucleus. Cytoplasm Melanosome. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P24452}. Cell projection, ruffle {ECO:0000250|UniProtKB:P24452}. Note=In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. {ECO:0000250|UniProtKB:P24452} |
| Tissue Location | Macrophages and macrophage-like cells. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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