癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Oxysterol binding protein like 1A Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9BXW6 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4065 |
| Calculated MW | 108470 Da |
| Gene Name | OSBPL1A |
| Aliases | OSBPL1A; Oxysterol Binding Protein Like 1A; ORP-1; ORP1; OSBPL1B; Oxysterol-Binding Protein-Related Protein 1; Oxysterol Binding Protein-Like 1B; OSBP-Related Protein 1; Oxysterol Binding Protein-Like 1A; OSBPL1; OSBP8 |
| Immunogen | A synthesized peptide derived from human ORP1 |
| Gene ID | 114876 |
|---|---|
| Other Names | Oxysterol-binding protein-related protein 1, ORP-1, OSBP-related protein 1, OSBPL1A (HGNC:16398) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | OSBPL1A (HGNC:16398) |
|---|---|
| Function | Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193). |
| Cellular Location | Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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