癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-RAS p21 protein activator 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P20936 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4125 |
| Calculated MW | 116403 Da |
| Gene Name | RASA1 |
| Aliases | RASA1; RAS P21 Protein Activator 1; P120GAP; GAP; Ras GTPase-Activating Protein 1; P120RASGAP; CM-AVM; P120; RASA; RAS P21 Protein Activator (GTPase Activating Protein) 1; P120 RAS GTPase Activating Protein; Capillary Malformation-Arteriovenous Malformation; Triphosphatase-Activating Protein; GTPase-Activating Protein; Ras P21 Protein Activator; CMAVM1; RASGAP; RasGAP; CMAVM; PKWS |
| Immunogen | A synthesized peptide derived from human RASA1 |
| Gene ID | 5921 |
|---|---|
| Other Names | Ras GTPase-activating protein 1, GAP, GTPase-activating protein, RasGAP, Ras p21 protein activator, p120GAP, RASA1, GAP, RASA |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RASA1 (HGNC:9871) |
|---|---|
| Synonyms | GAP, RASA |
| Function | GTPase-activating protein (GAP) that stimulates the intrinsic GTPase activity of Ras proteins, such as NRAS, facilitating their transition from the active GTP-bound state to the inactive GDP-bound state, thereby terminating Ras signaling. |
| Cellular Location | Cytoplasm. |
| Tissue Location | In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level) |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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