癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-SPINK5 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, ICC |
|---|---|
| Primary Accession | Q9NQ38 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4180 |
| Calculated MW | 120714 Da |
| Gene Name | SPINK5 |
| Aliases | SPINK5; Serine Peptidase Inhibitor Kazal Type 5; LEKTI; VAKTI; LETKI; NETS; NS; Lympho-Epithelial Kazal-Type-Related Inhibitor; Lymphoepithelial Kazal-Type-Related Inhibitor; Serine Protease Inhibitor Kazal-Type 5; FLJ21544; FLJ97536; FLJ97596 ; FLJ99794; Serine Protease Inhibitor, Kazal Type 5; DKFZp686K19184; DKFZP686K19184 |
| Immunogen | A synthesized peptide derived from human SPINK5 / LEKTI |
| Gene ID | 11005 |
|---|---|
| Other Names | Serine protease inhibitor Kazal-type 5, Lympho-epithelial Kazal-type-related inhibitor, LEKTI, Hemofiltrate peptide HF6478, Hemofiltrate peptide HF7665, SPINK5 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SPINK5 |
|---|---|
| Function | Serine protease inhibitor, probably important for the anti- inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation- involved proteases. Inhibits KLK5, its major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin. |
| Cellular Location | Secreted. |
| Tissue Location | Highly expressed in the thymus and stratum corneum. Also found in the oral mucosa, parathyroid gland, Bartholin's glands, tonsils, and vaginal epithelium. Very low levels are detected in lung, kidney, and prostate. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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