KD-Validated Anti-UFC1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9Y3C8 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4245 |
| Calculated MW | 19458 Da |
| Gene Name | UFC1 |
| Aliases | UFC1; Ubiquitin-Fold Modifier Conjugating Enzyme 1; HSPC155; Ubiquitin-Fold Modifier-Conjugating Enzyme 1; Ufm1-Conjugating Enzyme 1; NEDSG |
| Immunogen | A synthesized peptide derived from human UFC1 |
| Gene ID | 51506 |
|---|---|
| Other Names | Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1, UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941} |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941} |
|---|---|
| Function | E2-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776, PubMed:30626644, PubMed:34588452, PubMed:35394863, PubMed:36121123, PubMed:38383789). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776, PubMed:34588452, PubMed:38383789). Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy) (PubMed:27351204, PubMed:32160526, PubMed:35394863, PubMed:37036982, PubMed:38383789). |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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