癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Zinc fingers and homeoboxes 2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, ICC |
|---|---|
| Primary Accession | Q9Y6X8 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4270 |
| Calculated MW | 92307 Da |
| Gene Name | ZHX2 |
| Aliases | ZHX2; Zinc Fingers And Homeoboxes 2; KIAA0854; Zinc Fingers And Homeoboxes Protein; Zinc Finger And Homeodomain Protein; Alpha-Fetoprotein Regulator 1; Regulator Of AFP; AFP Regulator 1; AFR1; RAF; Zinc-Fingers And Homeoboxes 2; Transcription Factor ZHX2 |
| Immunogen | A synthesized peptide derived from human ZHX2 |
| Gene ID | 22882 |
|---|---|
| Other Names | Zinc fingers and homeoboxes protein 2, Alpha-fetoprotein regulator 1, AFP regulator 1, Regulator of AFP, Zinc finger and homeodomain protein 2, ZHX2, AFR1, KIAA0854, RAF |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZHX2 |
|---|---|
| Synonyms | AFR1, KIAA0854, RAF |
| Function | Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598} Note=Colocalizes with EFNB1 intracellular domain in the nucleus {ECO:0000250|UniProtKB:Q8C0C0} |
| Tissue Location | Ubiquitously expressed. Expressed in podocytes. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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