癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Thymidine Kinase 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P04183 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB3555 |
| Calculated MW | 25469 Da |
| Gene Name | TK1 |
| Aliases | TK1; Thymidine Kinase 1; Thymidine Kinase, Cytosolic; Cytosolic Thymidine Kinase; EC 2.7.1.21; Epididymis Secretory Sperm Binding Protein; Thymidine Kinase 1, Soluble; TK2 |
| Immunogen | A synthesized peptide derived from human Thymidine Kinase 1 |
| Gene ID | 7083 |
|---|---|
| Other Names | Thymidine kinase, cytosolic, 2.7.1.21, TK1 (HGNC:11830) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TK1 (HGNC:11830) |
|---|---|
| Function | Cell-cycle-regulated enzyme of importance in nucleotide metabolism (PubMed:9575153). Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate (PubMed:22385435). Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c- azido-3c-deoxythymidine (AZT) (PubMed:22385435). |
| Cellular Location | Cytoplasm. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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