癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Golgi reassembly stacking protein 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | Q9BQQ3 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB5580 |
| Calculated MW | 46482 Da |
| Gene Name | GORASP1 |
| Aliases | GORASP1; Golgi Reassembly Stacking Protein 1; GRASP65; Golgi Phosphoprotein 5; GOLPH5; P65; Golgi Reassembly-Stacking Protein Of 65 KDa; Golgi Reassembly Stacking Protein 1, 65kDa; Golgi Peripheral Membrane Protein P65; Golgi Reassembly-Stacking Protein 1; FLJ23443; Golgi Reassembly And Stacking Protein 1 |
| Immunogen | A synthesized peptide derived from human GRASP65 |
| Gene ID | 64689 |
|---|---|
| Other Names | Golgi reassembly-stacking protein 1, Golgi peripheral membrane protein p65, Golgi phosphoprotein 5, GOLPH5, Golgi reassembly-stacking protein of 65 kDa, GRASP65, GORASP1, GOLPH5, GRASP65 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GORASP1 |
|---|---|
| Synonyms | GOLPH5, GRASP65 |
| Function | Key structural protein of the Golgi apparatus (PubMed:33301566). The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (PubMed:33301566). Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (PubMed:33301566). However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (By similarity). Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (PubMed:16489344). Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (PubMed:21884936). |
| Cellular Location | Golgi apparatus, cis-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum- Golgi intermediate compartment membrane |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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