癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Keratin 10 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, ICC |
|---|---|
| Primary Accession | P13645 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB6105 |
| Calculated MW | 58827 Da |
| Gene Name | KRT10 |
| Aliases | KRT10; Keratin 10; K10; CK10; KPP; Keratin, Type I Cytoskeletal 10; Keratin 10, Type I; Cytokeratin 10; CK-10; Keratosis Palmaris Et Plantaris; Epidermolytic Hyperkeratosis; Cytokeratin-10; Keratin-10; BCIE; EHK2; BIE; EHK; IHL |
| Immunogen | A synthesized peptide derived from human Cytokeratin 10 |
| Gene ID | 3858 |
|---|---|
| Other Names | Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KRT10 (HGNC:6413) |
|---|---|
| Synonyms | KPP |
| Function | Structural component of intermediate filaments in suprabasal keratinocytes of stratified epithelia. Forms heteropolymers primarily with the type II keratin KRT1, and also with KRT2, assembling into intermediate filament networks that support terminal differentiation, mechanical resilience, and epidermal barrier formation. |
| Cellular Location | Secreted, extracellular space. Cell surface. Cytoplasm |
| Tissue Location | Seen in all suprabasal cell layers including stratum corneum. Expressed on the surface of lung cell lines (PubMed:19627498). Localized on the surface of desquamated nasal epithelial cells (at protein level) (PubMed:12427098) |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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