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>   首页   >   KD-Validated Anti-GST3 / GSTP1 Rabbit Monoclonal Antibody   

KD-Validated Anti-GST3 / GSTP1 Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P09211
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 23GB6420
Calculated MW 23356 Da
Gene Name GSTP1
Aliases GSTP1; Glutathione S-Transferase Pi 1; FAEES3; GSTP; GST3; Glutathione S-Transferase P; GST Class-Pi; EC 2.5.1.18; GSTP1-1; Fatty Acid Ethyl Ester Synthase III; Epididymis Secretory Protein Li 22; Deafness, X-Linked 7; HEL-S-22; DFN7; PI
Immunogen A synthesized peptide derived from human GST3 / GST pi
Additional Information
Gene ID 2950
Other Names Glutathione S-transferase P, 2.5.1.18, GST class-pi, GSTP1-1, GSTP1 (HGNC:4638), FAEES3, GST3

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name GSTP1 (HGNC:4638)
Synonyms FAEES3, GST3
Function Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1540159, PubMed:1567427, PubMed:8433974). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde (PubMed:38016474). Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration (PubMed:21668448).
Cellular Location Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization
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