KD-Validated Anti-GST3 / GSTP1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | P09211 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB6420 |
| Calculated MW | 23356 Da |
| Gene Name | GSTP1 |
| Aliases | GSTP1; Glutathione S-Transferase Pi 1; FAEES3; GSTP; GST3; Glutathione S-Transferase P; GST Class-Pi; EC 2.5.1.18; GSTP1-1; Fatty Acid Ethyl Ester Synthase III; Epididymis Secretory Protein Li 22; Deafness, X-Linked 7; HEL-S-22; DFN7; PI |
| Immunogen | A synthesized peptide derived from human GST3 / GST pi |
| Gene ID | 2950 |
|---|---|
| Other Names | Glutathione S-transferase P, 2.5.1.18, GST class-pi, GSTP1-1, GSTP1 (HGNC:4638), FAEES3, GST3 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GSTP1 (HGNC:4638) |
|---|---|
| Synonyms | FAEES3, GST3 |
| Function | Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1540159, PubMed:1567427, PubMed:8433974). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde (PubMed:38016474). Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration (PubMed:21668448). |
| Cellular Location | Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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