癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Cyclin dependent kinase 16 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q00536 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB1495 |
| Calculated MW | 55716 Da |
| Gene Name | CDK16 |
| Aliases | CDK16; Cyclin Dependent Kinase 16; PCTAIRE1; PCTGAIRE; PCTAIRE; PCTK1; Serine/Threonine-Protein; Kinase PCTAIRE-1; Cell Division Protein Kinase 16; PCTAIRE-Motif Protein Kinase; Cyclin-Dependent Kinase 16; EC 2.7.11.22; FLJ16665; Testis Secretory Sperm-Binding Protein Li 224n; Serine/Threonine-Protein Kinase; PCTAIRE Protein Kinase; EC 2.7.11 |
| Immunogen | A synthesized peptide derived from human PCTAIRE1 |
| Gene ID | 5127 |
|---|---|
| Other Names | Cyclin-dependent kinase 16, 2.7.11.22, Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1, CDK16, PCTAIRE1, PCTK1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CDK16 |
|---|---|
| Synonyms | PCTAIRE1, PCTK1 |
| Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro). |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q63686} Cell membrane; Peripheral membrane protein; Cytoplasmic side. Synapse, synaptosome {ECO:0000250|UniProtKB:Q63686}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY |
| Tissue Location | Detected in pancreas islets (at protein level). Detected in brain and pancreas. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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