癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-TNF Alpha Induced Protein 8 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | O95379 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB2315 |
| Calculated MW | 23003 Da |
| Gene Name | TNFAIP8 |
| Aliases | TNFAIP8; TNF Alpha Induced Protein 8; MDC-3.13; SCC-S2; GG2-1; Head And Neck Tumor And Metastasis-Related Protein; Tumor Necrosis Factor Alpha-Induced Protein 8; NF-Kappa-B-Inducible DED-Containing Protein; TNF-Induced Protein GG2-1; NDED; Tumor Necrosis Factor, Alpha-Induced Protein 8; Tumor Necrosis Factor, Alpha Induced Protein 8; TNF Alpha-Induced Protein 8; SCCS2 |
| Immunogen | A synthesized peptide derived from human TNFAIP8 |
| Gene ID | 25816 |
|---|---|
| Other Names | Tumor necrosis factor alpha-induced protein 8, TNF alpha-induced protein 8, Head and neck tumor and metastasis-related protein, MDC-3.13, NF-kappa-B-inducible DED-containing protein, NDED, SCC-S2, TNF-induced protein GG2-1, TNFAIP8 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TNFAIP8 |
|---|---|
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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