癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-SMYD3 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9H7B4 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB2260 |
| Calculated MW | 49097 Da |
| Gene Name | SMYD3 |
| Aliases | SMYD3; SET And MYND Domain Containing 3; ZNFN3A1; ZMYND1; KMT3E; Zinc Finger MYND Domain-Containing Protein 1; Histone-Lysine N-Methyltransferase SMYD3 ; SET And MYND Domain-Containing Protein 3; Zinc Finger, MYND Domain Containing 1; Zinc Finger Protein, Subfamily 3A (MYND Domain Containing), 1; EC 2.1.1.354; EC 2.1.1.43; BA74P14.1; EC 2.1.1 |
| Immunogen | A synthesized peptide derived from human SMYD3 |
| Gene ID | 64754 |
|---|---|
| Other Names | Histone-lysine N-methyltransferase SMYD3, 2.1.1.354 {ECO:0000255|PROSITE-ProRule:PRU00907, ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:22419068}, SET and MYND domain-containing protein 3, Zinc finger MYND domain-containing protein 1, SMYD3, ZMYND1, ZNFN3A1 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SMYD3 |
|---|---|
| Synonyms | ZMYND1, ZNFN3A1 |
| Function | Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation (PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4 (PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex (PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences (PubMed:15235609). |
| Cellular Location | Cytoplasm. Nucleus. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M. |
| Tissue Location | Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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