癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-Creatine Kinase B type Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P12277 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB4350 |
| Calculated MW | 42644 Da |
| Gene Name | CKB |
| Aliases | CKB; Creatine Kinase B; CKBB; Creatine Phosphokinase B-Type; Creatine Kinase Brain-Type; Creatine Kinase B Chain; Creatine Kinase B-Type; Brain Creatine Kinase; EC 2.7.3.2; CPK-B; B-CK; Epididymis Secretory Protein Li; Epididymis Luminal Protein 211; Creatine Kinase, Brain; Creatine Kinase Brain; HEL-S-29; EC 2.7.3; HEL-211; BCK |
| Immunogen | A synthesized peptide derived from human Creatine kinase B type |
| Gene ID | 1152 |
|---|---|
| Other Names | Creatine kinase B-type, 2.7.3.2, Brain creatine kinase, B-CK, Creatine kinase B chain, Creatine phosphokinase B-type, CPK-B, CKB (HGNC:1991), CKBB |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CKB (HGNC:1991) |
|---|---|
| Synonyms | CKBB |
| Function | Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation (By similarity). During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N- phosphocreatine as heat without performing any mechanical or chemical work (By similarity). |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q04447}. Mitochondrion {ECO:0000250|UniProtKB:Q04447}. Cell membrane. Note=Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region {ECO:0000250|UniProtKB:Q04447} |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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