癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-LTBR mouse monoclonal antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, ICC |
|---|---|
| Primary Accession | P36941 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB6730 |
| Calculated MW | 46709 Da |
| Gene Name | LTBR |
| Aliases | LTBR; Lymphotoxin Beta Receptor; TNFRSF3; TNFCR; TNF-R-III; TNFR2-RP; TNFR-RP; D12S370; Tumor Necrosis Factor Receptor Superfamily Member 3; Tumor Necrosis Factor Receptor 2-Related Protein; Tumor Necrosis Factor Receptor Type III; Tumor Necrosis Factor C Receptor; TNFR3; Lymphotoxin Beta Receptor (TNFR Superfamily, Member 3); TNFR Superfamily, Member 3; Lymphotoxin-Beta Receptor; Lymphotoxin B Receptor; LT-BETA-R; TNF-RIII; TNFR-III |
| Immunogen | Recombinant protein of human LTBR |
| Gene ID | 4055 |
|---|---|
| Other Names | Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LTBR |
|---|---|
| Synonyms | D12S370, TNFCR, TNFR3, TNFRSF3 |
| Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT (PubMed:24248355). Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)) (PubMed:24248355). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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