癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-CFAP298 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC |
|---|---|
| Primary Accession | P57076 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB7915 |
| Calculated MW | 33224 Da |
| Gene Name | CFAP298 |
| Aliases | CFAP298; Cilia And Flagella Associated Protein 298; C21orf48; C21orf59; DNAAF16; CILD26; FBB18; Kur; Cilia- And Flagella-Associated Protein 298; Dynein Axonemal Assembly Factor 16; Protein Kurly Homolog; FLJ20467; Prostate Cancer Upregulated Protein 1; Chromosome 21 Open Reading Frame 48; Chromosome 21 Open Reading Frame 59; Kurly Homolog (Zebrafish); UPF0769 Protein C21orf59; Kurly Homolog |
| Immunogen | Recombinant protein of human C21orf59 |
| Gene ID | 56683 |
|---|---|
| Other Names | Cilia- and flagella-associated protein 298, Protein kurly homolog, CFAP298 (HGNC:1301), C21orf48, C21orf59 |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CFAP298 (HGNC:1301) |
|---|---|
| Synonyms | C21orf48, C21orf59 |
| Function | Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0A1L8HCK2}. Note=Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization {ECO:0000250|UniProtKB:Q5U3Z0} |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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