癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-CAMLG Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P49069 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB7950 |
| Calculated MW | 32953 Da |
| Gene Name | CAMLG |
| Aliases | CAMLG; Calcium Modulating Ligand; CAML; GET2; Guided Entry Of Tail-Anchored Proteins Factor CAMLG; Calcium Signal-Modulating Cyclophilin Ligand; Calcium-Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein; Calcium-Signal Modulating Cyclophilin Ligand; CDG2Z |
| Immunogen | Recombinant protein of human CAMLG |
| Gene ID | 819 |
|---|---|
| Other Names | Guided entry of tail-anchored proteins factor CAMLG, Calcium signal-modulating cyclophilin ligand {ECO:0000312|HGNC:HGNC:1471}, CAMLG (HGNC:1471) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CAMLG (HGNC:1471) |
|---|---|
| Function | Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (PubMed:23041287, PubMed:24392163, PubMed:27226539). Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (PubMed:23041287, PubMed:24392163, PubMed:27226539). Required for the stability of GET1 (PubMed:32187542). Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium (PubMed:7522304). Essential for the survival of peripheral follicular B cells (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. Highest levels in brain, testis and ovary |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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