癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-FAF1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9UNN5 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB8245 |
| Calculated MW | 73954 Da |
| Gene Name | FAF1 |
| Aliases | FAF1; Fas Associated Factor 1; UBXD12; UBXN3A; HFAF1; CGI-03; HFAF1s; Fas (TNFRSF6) Associated Factor 1; UBX Domain-Containing Protein 12; UBX Domain-Containing Protein 3A; TNFRSF6-Associated Factor 1; FAS-Associated Factor 1; UBX Domain Protein 3A |
| Immunogen | Recombinant protein of human FAF1 |
| Gene ID | 11124 |
|---|---|
| Other Names | FAS-associated factor 1, hFAF1, UBX domain-containing protein 12, UBX domain-containing protein 3A, FAF1, UBXD12, UBXN3A |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | FAF1 |
|---|---|
| Synonyms | UBXD12, UBXN3A |
| Function | Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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