癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KD-Validated Anti-GALE Mouse Monoclonal Antibody
Mouse monoclonal antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q14376 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB13050 |
| Calculated MW | 38282 Da |
| Gene Name | GALE |
| Aliases | GALE; UDP-Galactose-4-Epimerase; UDP-Glucose 4-Epimerase; SDR1E1; Short Chain Dehydrogenase/Reductase Family 1E, Member 1; UDP-N-Acetylgalactosamine 4-Epimerase; UDP-N-Acetylglucosamine 4-Epimerase; Galactose-4-Epimerase, UDP-; UDP-GalNAc 4-Epimerase; UDP-GlcNAc 4-Epimerase; Galactowaldenase; EC 5.1.3.2; Epididymis Secretory Sperm Binding Protein; UDP Galactose-4'-Epimerase; UDP-Galactose 4-Epimerase; EC 5.1.3.7; EC 5.1.3 47; THC13 |
| Immunogen | Recombinant protein of human GALE |
| Gene ID | 2582 |
|---|---|
| Other Names | UDP-glucose 4-epimerase, 5.1.3.2, Galactowaldenase, UDP-N-acetylgalactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, 5.1.3.7, UDP-galactose 4-epimerase, GALE (HGNC:4116) |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GALE (HGNC:4116) |
|---|---|
| Function | Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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